Definition

A synthetic peptide vaccine composed of four synthetic peptide epitopes of the tumor-associated antigen (TAA) labyrinthin, with potential immunomodulating and antineoplastic activities. Upon vaccination with labyrinthin peptide vaccine LabVax 3(22)-23, the labyrinthin peptides may stimulate the immune system to mount B-cell and cytotoxic T-lymphocyte (CTL) responses against labryrinthin-expressing tumor cells. Labyrinthin is expressed on the surface of essentially all adenocarcinomas, but is not expressed in normal, healthy cells.