Single Biggest Cancer Dictionary in the World
What is
Hsp90 inhibitor TQB3474
?Pronunciation: /hsp* ˈnaɪnti ˌɪnˈhɪbətər tqb* θri ˈθaʊzənd, fɔr ˈhənərd ənd seventy-four*/
Hsp90 inhibitor TQB3474
Definition
An inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity. Upon administration, Hsp90 inhibitor TQB3474 specifically blocks Hsp90, which inhibits its chaperone function and promotes the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may lead to an inhibition of tumor cell proliferation. Hsp90, a chaperone complex protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.