Single Biggest Cancer Dictionary in the World
What is HPV-6-targeting immunotherapeutic vaccine INO-3106?
Pronunciation: /hpv* sɪks ˈtɑrgətɪŋ immunotherapeutic* ˌvækˈsin ino* θri ˈθaʊzənd, wən ˈhənərd ənd sɪks/
HPV-6-targeting immunotherapeutic vaccine INO-3106
Definition
A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies.