Single Biggest Cancer Dictionary in the World
What is HLA-A*2402-restricted multipeptide vaccine S-488410?
Pronunciation: /hla* ə tu ˈθaʊzənd, fɔr ˈhənərd ənd tu riˈstrɪktɪd multipeptide* ˌvækˈsin ɛs fɔr ˈhənərd ənd eighty-eight* ˈθaʊzənd, fɔr ˈhənərd ənd tɛn/
HLA-A*2402-restricted multipeptide vaccine S-488410
Definition
A cancer vaccine composed of HLA-*2402-restricted epitopic peptides derived from three cancer/testis (CT) antigens, with potential antineoplastic activity. Upon subcutaneous administration, HLA-A*2402-restricted multipeptide vaccine S-488410 may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing these CT antigens. CT antigens, normally expressed only in germ cells of the testis, are overexpressed in a wide variety of human cancers.