Single Biggest Cancer Dictionary in the World
What is halichondrin analogue E7130?
Pronunciation: /halichondrin* ˈænəˌlɔg i ˈsɛvən ˈθaʊzənd, wən ˈhənərd ənd ˈθərˌdi/
halichondrin analogue E7130
Definition
A halichondrin analogue derived from a marine sponge with potential antineoplastic activity. Upon intravenous infusion, halichondrin analogue E7130 may bind to the vinca domain of tubulin and inhibit the polymerization of tubulin and the assembly of microtubules, thereby inhibiting mitotic spindle assembly and inducing cell cycle arrest at the G2/M phase.