Definition

An orally available, dietary supplement consisting of Taiwan green propolis dissolved in edible oil, with potential antibacterial, anti-inflammatory, antioxidant and anti-mucositis activities. Depending on location and seasons, a variety of phenolic acids, flavonoids, esters, diterpenes, sesquiterpenes, lignans, aromatic aldehydes, alcohols, amino acids, fatty acids, vitamins and minerals have been found in propolis, which is produced by bees using beeswax and saliva. The anti-mucositis effects of propolis may be attributable to the antibacterial, anti-inflammatory, and antioxidant activities of polyphenolic compounds including flavonoids and phenolic acids. Upon administration, green propolis supplement may kill bacteria thus potentially preventing inflammation of the mucosal membranes, thereby decreasing radiation-induced oral mucositis. In addition, propolis may act as antioxidant and scavenge free radicals. This may inhibit cellular oxidation and prevent free radical damage to cells.