Definition

An ophthalmic solution containing a prodrug of levcromakalim, a modulator of the adenosine triphosphate (ATP)-sensitive potassium (KATP) channel, with potential vasodilating and episcleral venous pressure (EVP)-lowering activities. Upon application into the eye, foslevcromakalim is converted to levcromakalim, which dilates blood vessels by opening the KATP channel. This lowers both EVP and elevated intraocular pressure (IOP).