Definition

A radioconjugate composed of the amyloid-beta-binding peptide RD2 labeled with the radionuclide fluorine F 18, with potential amyloid-beta peptide imaging activity upon positron emission topography (PET)/computed tomography (CT). Upon administration of fluorine F 18 RD2, RD2 targets and binds to amyloid-beta. Upon PET/CT imaging, amyloid-beta plaques can be visualized and detected. Amyloid-beta is a key component in plaque formation in Alzheimer’s disease. Elevated plasma levels of amyloid-beta are also associated with some cancers.