Definition

A radioconjugate composed of para-chloro-2-fluoroethyletomidate (CETO) conjugated to the radioisotope fluorine F 18 (18F), with potential application in adrenal imaging during positron emission tomography/computed tomography (PET/CT). Upon administration of [18F]CETO, the CETO moiety targets, binds to and is taken up by the adrenocortical cells located on the adrenal glands. Upon PET/CT, primary aldosteronism and adrenal tumors, such as cortisol producing adrenocortical adenoma and non-functioning adrenocortical carcinoma, can be visualized and detected during PET/CT imaging.