Single Biggest Cancer Dictionary in the World
What is fluorine F 18 integrin alpha v beta 6-targeted binding peptide?
Pronunciation: /ˈflʊˌrin ɛf ˈeɪˈtin integrin* ˈælfə vi ˈbeɪtə sɪks ˈtɑrgətɪd ˈbaɪndɪŋ ˈpɛpˌtaɪd/
fluorine F 18 integrin alpha v beta 6-targeted binding peptide
Definition
A radiotracer composed of an integrin alphaVbeta6 (aVb6) binding peptide (BP) radiolabeled with the radionuclide fluorine F 18, with potential integrin aVb6 imaging activity using positron emission tomography (PET). Upon administration, the fluorine F 18 integrin aVb6-targeted peptide selectively binds to integrin aVb6-positive cancer cells. During PET, aVb6-expressing tumor cells can be visualized and the degree of tumor growth can be determined. Integrin aVb6, a cell adhesion and signaling receptor, is upregulated in certain cancer cell types and has been associated with increased proliferation, migration and invasion of tumor cells.