Definition

A radioconjugate composed of florbetapir, an amyloid-binding ligand, labeled with the positron-emitting isotope fluorine F 18, that may be used for positron emission tomography (PET) detection of beta-amyloid neuritic plaques. Upon administration, fluorine F 18 florbetapir targets and binds to beta-amyloid neuritic plaques. Upon PET, amyloid neuritic plaques can be visualized, and the amount of amyloid neuritic plaque present may be indicative of Alzheimer’s disease (AD) or other types of neurologic conditions.