Single Biggest Cancer Dictionary in the World
What is FGF401 inhibitor FGF401?
Pronunciation: /fgf* fɔr ˈhənərd ənd wən ˌɪnˈhɪbətər fgf* fɔr ˈhənərd ənd wən/
FGF401 inhibitor FGF401
Definition
An inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.