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What is Epstein-Barr virus gp350-ferritin nanoparticle vaccine with saponin-based adjuvant?
Pronunciation: /ˈɛpˌstin bɑr ˈvaɪrəs gp* θri ˈhənərd ənd ˈfɪfti ferritin* nanoparticle* ˌvækˈsin wɪθ saponin* beɪst adjuvant*/
Epstein-Barr virus gp350-ferritin nanoparticle vaccine with saponin-based adjuvant
Definition
A ferritin-based, nanoparticle vaccine consisting of the Epstein-Barr Virus (EBV) envelop glycoprotein gp350 and a saponin-based adjuvant, with potential immunizing activity against EBV. Upon intramuscular administration of EBV gp350-ferritin nanoparticle vaccine with saponin-based adjuvant, the EBV gp350 may activate both humoral and cellular immune responses which may result in protection against EBV infection. EBV, a ubiquitous human herpes virus, is associated with infectious mononucleosis and various malignancies, including nasopharyngeal carcinoma, Hodgkin disease, non-Hodgkin lymphoma, and other lymphomas.