Definition

An orally bioavailable, proprietary botanical-based formulation and nutritional supplement consisting of three botanical extracts, including broccoli powder and curcumin, that may be used to reduce taxane-induced side effects and toxicities. Upon oral administration, epidiferphane may be able to decrease inflammation and pain by reducing cytokine levels. It may also reduce taxane-mediated toxicities such as anemia, neutropenia, peripheral neuropathy, and protect the endogenous neural stem cell population against destruction thereby preventing memory problems associated with the loss of neural stem cells.