Single Biggest Cancer Dictionary in the World

What is

DNA minor groove binding agent PM060184

?

Pronunciation: /ˈdiˌɛˈneɪ ˈmaɪnər gruv ˈbaɪndɪŋ ˈeɪʤənt piɛm ˈsɪksti ˈθaʊzənd, wən ˈhənərd ənd eighty-four*/

DNA minor groove binding agent PM060184

Definition

A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.