Single Biggest Cancer Dictionary in the World
What is
DNA minor groove binding agent PM060184
?Pronunciation: /ˈdiˌɛˈneɪ ˈmaɪnər gruv ˈbaɪndɪŋ ˈeɪʤənt piɛm ˈsɪksti ˈθaʊzənd, wən ˈhənərd ənd eighty-four*/
DNA minor groove binding agent PM060184
Definition
A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.