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What is
dihydro-5-azacytidine
?Pronunciation: /dihydro* faɪv azacytidine*/
dihydro-5-azacytidine
Definition
A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.