Single Biggest Cancer Dictionary in the World
What is dendritic cell-gp100-MART-1 antigen vaccine?
Pronunciation: /dɛnˈdrɪtɪk sɛl gp* wən ˈhənərd mɑrt wən ˈæntəʤən ˌvækˈsin/
dendritic cell-gp100-MART-1 antigen vaccine
Definition
An autologous dendritic cell vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 antigen (a melanoma antigen recognized by T-cells); both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells.