Single Biggest Cancer Dictionary in the World
What is cord blood-derived expanded allogeneic natural killer cells?
Pronunciation: /kɔrd bləd dəraɪvd ɪkˈspændɪd allogeneic* ˈnæʧərəl ˈkɪlər sɛlz/
cord blood-derived expanded allogeneic natural killer cells
Definition
A preparation of human umbilical cord blood (UCB)-derived and ex vivo-expanded allogeneic natural killer (NK) cells, with immunomodulating and cytotoxic activities. Upon infusion of the cord blood-derived expanded allogeneic NK cells, these cells recognize and bind to tumor cells, and secrete perforins, granzymes, and cytokines, which cause cancer cell lysis.