Single Biggest Cancer Dictionary in the World

What is

copper Cu 64 SAR-bombesin

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Pronunciation: /ˈkɑpər cu* sixty-four* sɑr bombesin*/

copper Cu 64 SAR-bombesin

Definition

A radioconjugate containing bombesin (BBN), a tetra-decapeptide that binds with high affinity to the gastrin-releasing peptide receptor (GRPR), and linked, by the sarcophagine chelator (SAR), to the radionuclide copper Cu 64, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT). Upon administration of copper Cu 64 SAR-BBN, the BBN moiety targets and binds to GRPR. Upon PET/CT, GRPR-expressing tumor cells can be visualized. GRPR, also called bombesin receptor 2 (BB2), is a seven-transmembrane G protein-coupled receptor belonging to the bombesin receptor family. It is overexpressed in certain types of cancers.