Definition

A traditional Chinese medicine (TCM) formulation containing multiple flavones and their glycosides, phenolic and polyphenolic acids, and sesquiterpene lactones, with potential anti-inflammatory, immunomodulating and antineoplastic activities. Upon administration of Centipeda minima decoction, the active ingredients may modulate the cell cycle, induce apoptosis and inhibit tumor cell proliferation. It may also modulate the immune system by reducing the production of pro-inflammatory cytokines and inhibiting Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling.