Single Biggest Cancer Dictionary in the World
What is
BMS-184476
?Pronunciation: /bms* wən ˈhənərd ənd eighty-four* ˈθaʊzənd, fɔr ˈhənərd ənd seventy-six*/
BMS-184476
Definition
A 7-methylthiomethyl ether derivative of paclitaxel with antineoplastic activity. BMS-184476 binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. (NCI)