Single Biggest Cancer Dictionary in the World
What is
BCR signaling pathway inhibitor DZD8586
?Pronunciation: /bcr* ˈsɪgnəlɪŋ ˈpæθˌweɪ ˌɪnˈhɪbətər dzd* eɪt ˈθaʊzənd, faɪv ˈhənərd ənd eighty-six*/
BCR signaling pathway inhibitor DZD8586
Definition
An inhibitor of the B-cell antigen receptor (BCR) signaling pathway, with potential antineoplastic activity. Upon administration, BCR signaling pathway inhibitor DZD8586 blocks signaling through the BCR signaling pathway. This prevents the proliferation of malignant B cells in which the BCR signaling pathway is overactivated. DZD8586 is able to cross the blood-brain barrier (BBB) and thus potentially useful in the treatment of central nervous system (CNS) metastases.