Single Biggest Cancer Dictionary in the World
What is autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine?
Pronunciation: /autologous* dɛnˈdrɪtɪk sɛl allogeneic* ˌmɛləˈnoʊmə ˈtumər sɛl lysate* ˌvækˈsin/
autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine
Definition
A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis.