Single Biggest Cancer Dictionary in the World
What is
autologous cytotoxic T lymphocytes exposed to dendritic cells loaded with 6B11 anti-idiotype minibody
?Pronunciation: /autologous* cytotoxic* ti ˈlɪmfəˌsaɪts ɪkˈspoʊzd tɪ dɛnˈdrɪtɪk sɛlz ˈloʊdɪd wɪθ sɪks bi ˈilɛvən ˈænˌti idiotype* minibody*/
autologous cytotoxic T lymphocytes exposed to dendritic cells loaded with 6B11 anti-idiotype minibody
Definition
A preparation of autologous cytotoxic T lymphocytes (CTLs) that are exposed, ex vivo, to autologous dendritic cells (DCs) loaded with the anti-idiotype minibody 6B11, which mimics the epithelial ovarian tumor-associated antigen (TAA), OC166-9, with potential immunostimulatory and antineoplastic activities. Upon administration, the CTLs exposed to DCs loaded with 6B11 anti-idiotype minibody target and kill autologous ovarian cells expressing the TAA.