Single Biggest Cancer Dictionary in the World
What is aurora kinase inhibitor SNS-314?
Pronunciation: /ərˈɔrə kinase* ˌɪnˈhɪbətər sns* θri ˈhənərd ənd ˌfɔrˈtin/
aurora kinase inhibitor SNS-314
Definition
A synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis.