Single Biggest Cancer Dictionary in the World

What is

allogeneic GM-CSF-based myeloma cell vaccine

?

Pronunciation: /allogeneic* gm* csf* beɪst myeloma* sɛl ˌvækˈsin/

allogeneic GM-CSF-based myeloma cell vaccine

Definition

An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens.