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What is activated polyethylene glycol/polyethyleneimine-based surgical sealant?
Pronunciation: /ˈæktɪˌveɪtɪd ˌpɑˌliˈɛθəˌlin ˈglaɪˌkɔl polyethyleneimine* beɪst ˈsərʤɪkəl ˈsilənt/
activated polyethylene glycol/polyethyleneimine-based surgical sealant
Definition
A surgical sealant composed of activated polyethylene glycol (PEG) and polyethyleneimine (PEI) that can be used to seal tears in the dura during spinal surgery in order to prevent cerebrospinal fluid (CSF) leakage. It may also minimize dural adhesions and scarring by providing a protective shield between the dura and surrounding tissue.