Single Biggest Cancer Dictionary in the World

What is 13-deoxydoxorubicin?

Pronunciation: /ˈθərˈtin deoxydoxorubicin*/

13-deoxydoxorubicin

Definition

An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.