Definition

An orally bioavailable east Asian herbal supplement, with potential gastro- and neuro-protective, immunostimulatory, anti-inflammatory, anti-cancer, anti-cachexic and antioxidant activities. Sipjeondaebo-tang is comprised of various components, including Angelica root (Angelicae Gigantis Radix), the rhizome of Cnidium officinale Makino (Cnidii Rhizoma), Radix Paeoniae, Rehmannia glutinosa root (Rehmanniae Radix Preparata), Ginseng root (Ginseng Radix Alba), Atractylodes lancea root (Atractylodis Rhizoma Alba), the dried sclerotia of Poria cocos (Poria cocos Sclerotium), Licorice root (Glycyrrhizae Radix), Astragalus root (Astragali Radix), and the dried bark of Cinnamomum verum (Cinnamomi Cortex). Upon administration, and although the exact mechanism of action has yet to be fully elucidated, sipjeondaebo-tang may exert its effect through the various mechanism of actions that may be attributed to the different herbs.