Single Biggest Cancer Dictionary in the World

What is ROS1 inhibitor JYP0322?

Pronunciation: /rɔs wən ˌɪnˈhɪbətər jyp* θri ˈhənərd ənd tˈwɛntiˌtu/

ROS1 inhibitor JYP0322

Definition

An orally available selective inhibitor of the receptor tyrosine kinase c-ros oncogene 1 (ROS1), with potential antineoplastic activity. Upon oral administration, ROS1 inhibitor JYP0322 targets, binds to and inhibits ROS1. This inhibits proliferation of ROS1-driven tumor cells. ROS1, overexpressed, rearranged and/or mutated in certain cancer cells, plays a key role in cell growth and survival of various types of cancer cells.