Single Biggest Cancer Dictionary in the World
What is lestaurtinib?
Pronunciation: /lestaurtinib*/
lestaurtinib
Definition
An orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3.