Single Biggest Cancer Dictionary in the World

What is iodine I 131 tositumomab?

Pronunciation: /ˈaɪəˌdaɪn aɪ wən ˈhənərd ənd thirty-one* tositumomab*/

iodine I 131 tositumomab

Definition

A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity.