Single Biggest Cancer Dictionary in the World
What is glioma-associated antigen peptide-pulsed autologous dendritic cell vaccine?
Pronunciation: /glioma* əˈsoʊʃiˌeɪtəd ˈæntəʤən ˈpɛpˌtaɪd pulsed* autologous* dɛnˈdrɪtɪk sɛl ˌvækˈsin/
glioma-associated antigen peptide-pulsed autologous dendritic cell vaccine
Definition
A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against GAA peptide-expressing glioma cells, resulting in tumor cell lysis.