Single Biggest Cancer Dictionary in the World
What is gallium Ga 68-labeled MLN6907?
Pronunciation: /ˈgæliəm ˈʤɔrʤə sixty-eight* ˈleɪbəld mln* sɪks ˈθaʊzənd, naɪn ˈhənərd ənd ˈsɛvən/
gallium Ga 68-labeled MLN6907
Definition
A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography (PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic neurons in the brain, that is also overexpressed on the surface of a variety of cancer cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.