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What is anti-IL-11 monoclonal antibody 9MW3811?
Pronunciation: /ˈænˌti ɪl ˈilɛvən ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi naɪn mw* θri ˈθaʊzənd, eɪt ˈhənərd ənd ˈilɛvən/
anti-IL-11 monoclonal antibody 9MW3811
Definition
A humanized monoclonal antibody directed against interleukin-11 (IL-11), with potential anti-fibrotic and antineoplastic activities. Upon administration, anti-IL-11 monoclonal antibody 9MW3811 targets and binds to IL-11. This prevents the binding of IL-11 to interleukin-11 receptor subunit alpha (IL-11RA), and inhibits IL-11-mediated signaling via the gp130/IL-11RA receptor complex. This may decrease fibrosis and inhibit tumor cell proliferation. IL-11, a member of the IL-6 family of cytokines, is upregulated in some fibro-inflammatory diseases and cancers.