Single Biggest Cancer Dictionary in the World
What is anti-CD19 monoclonal antibody MDX-1342?
Pronunciation: /ˈænˌti ˈsiˈdi ˈnaɪnˈtin ˌmɑnəˈkloʊnəl ˈæntɪˌbɑdi mdx* wən ˈθaʊzənd, θri ˈhənərd ənd forty-two*/
anti-CD19 monoclonal antibody MDX-1342
Definition
A fully human anti-CD19 monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential antineoplastic activity. Anti-CD19 monoclonal antibody MDX-1342 binds to CD19, depleting and eliminating CD19-expressing B cells. CD19 is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.