Definition

An allogeneic, off-the-shelf, preparation of purified human glial progenitor cells, with potential neuro-regenerative activity. Upon unilateral transplantation into spinal cord demyelinated lesions, the glial progenitor cells may integrate into the spinal cord lesion sites and differentiate into astrocytes and oligodendrocytes. Astrocytes are specialized neuroglial cells that perform many neuroprotective functions. Oligodendrocytes produce myelin and may repair damage in neurodegenerative diseases involving damaged or destroyed oligodendrocytes and myelin deficiency, such as transverse myelitis.