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What is allogeneic dendritic cell-myeloma idiotype vaccine?
Pronunciation: /allogeneic* dɛnˈdrɪtɪk sɛl myeloma* idiotype* ˌvækˈsin/
allogeneic dendritic cell-myeloma idiotype vaccine
Definition
A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis.