Definition

A substance that binds to a protein called TIGIT, which is found on T cells and some other immune cells and helps keep the body’s immune response from being too strong. TIGIT may also keep T cells from killing cancer cells. Tiragolumab blocks TIGIT, which may help the immune system kill cancer cells. It is being studied in the treatment of some types of cancer. Tiragolumab is a type of monoclonal antibody and a type of immune checkpoint inhibitor.