Definition

A drug used to treat adults with multiple myeloma that came back or did not get better after treatment with at least four other anticancer therapies, including an immunomodulating agent, a proteasome inhibitor, and an anti-CD38 monoclonal antibody. Teclistamab binds to a protein called CD3, which is found on T cells (a type of white blood cell). It also binds to a protein called BCMA, which is found on myeloma cells and some B cells (another type of white blood cell). This may help the immune system kill cancer cells. Teclistamab is a type of bispecific monoclonal antibody. Also called Tecvayli.