Definition

Stage IV is divided into stages IVA and IVB. In stage IVA, cancer has spread to the portal vein or hepatic artery or to two or more organs or structures other than the liver. Cancer may have spread to one to three nearby lymph nodes. In stage IVB, cancer may have spread to nearby organs or structures. Cancer has spread to (1) four or more nearby lymph nodes; or (2) other parts of the body, such as the peritoneum and liver.