Definition

A drug used with other drugs in adults to prevent nausea and vomiting caused by chemotherapy. Rolapitant hydrochloride blocks the action of a certain chemical in the central nervous system that may trigger nausea and vomiting. Blocking this chemical may lessen nausea and vomiting. Rolapitant hydrochloride is a type of antiemetic and a type of substance P/neurokinin 1 receptor antagonist. Also called Varubi.