Definition

A drug used to treat adults and children with certain types of solid tumors that have spread or cannot be removed by surgery and have the NTRK gene fusion. It is also being studied in the treatment of other types of cancer. Larotrectinib sulfate blocks the TRK protein, which may help keep cancer cells from growing and may kill them. It is a type of tyrosine kinase inhibitor. Also called LOXO-101, Trk inhibitor LOXO-101, and Vitrakvi.