Definition

A gene that makes one of the three subunits of a protein involved in cell growth, cell movement, and cell attachment. This protein helps protect the skin from damage and may be involved in wound healing and in the formation of tooth enamel and the cornea (the clear outer covering of the eye). Mutations (changes) in the LAMC2 gene have been found in an inherited condition called junctional epidermolysis bullosa, which causes the skin to tear and blister easily. People with this condition have an increased risk of developing skin cancer.